IDStewardship

  • Home
  • Articles
  • LEARN ANTIBIOTICS
  • Study Guide
  • Resources
  • Q&A
  • #ASPchat
  • Contributors
  • About

Clarithromycin

Clarithromycin

KEY POINTS

  • Clarithromycin (Biaxin) is a macrolide antibiotic that works against susceptible organisms by binding to the 50S ribosomal subunit, which results in protein inhibition
  • Uses include upper respiratory tract infection, Lyme disease, H. pylori, Mycobacterial infections, and more
    • Usual dose of immediate release is 250 to 500mg twice daily
      • Adjust dose when CrCl < 30mL/min
  • Two major side effects to beware are altered cardiac conduction & hepatic effects
  • Beware drug-drug interactions, clarithromycin is a major CYP3A4 substrate and strong inhibitor of CYP3A4
    • In general clarithromycin and erythromycin are used less frequently than azithromycin, because azithromycin has a more favorable adverse effect profile and less drug-drug interactions

RESOURCES

  • Clarithromycin Package Insert
  • H. pylori Guideline – American College of Gastroenterology
  • Diagnosis, Treatment and Prevention of Nontuberculous Mycobacterial Diseases
  • Opportunistic Infections Guideline – AIDSinfo.gov
  • IDSA Practice Guidelines

Free Antibiotic Cheat Sheet

Study Guide

  • Pharmacotherapy Study Guide
  • Acyclovir (Zovirax)
  • Albendazole (Albenza)
  • Amikacin
  • Aminoglycosides
  • Amphotericin B (Fungizone, Abelcet, Ambisome)
  • Amoxicillin (Amoxil)
  • Amoxicillin-Clavulanic Acid (Augmentin)
  • Ampicillin
  • Ampicillin-sulbactam (Unasyn)
  • Anidulafungin (Eraxis)
  • Artesunate
  • Atovaquone (Mepron)
  • Azithromycin (Zithromax, Zmax)
  • Aztreonam (Azactam, Cayston)
  • Bacitracin
  • Baloxavir marboxyl (Xofluza)
  • Bamlanivimab
  • Baricitinib (Olumiant)
  • Bebtelovimab
  • Bezlotoxumab (Zinplava)
  • Brincidofovir (Tembexa)
  • Casirivimab and Imdevimab (REGEN-COV)
  • Caspofungin (Cancidas)
  • Cefazolin (Ancef)
  • Cefepime
  • Cefiderocol
  • Ceftaroline
  • Ceftazidime
  • Ceftazidime-avibactam
  • Ceftolozane-Tazobactam
  • Ceftriaxone
  • Cefoxitin
  • Cephalexin
  • Cidofovir
  • Ciprofloxacin
  • Clarithromycin
  • Clindamycin
  • Colistin (colistimethate)
  • Cycloserine
  • Dalbavancin
  • Daptomycin
  • Delafloxacin
  • Dicloxacillin
  • Doripenem
  • Doxycycline
  • Elbasvir/ grazoprevir
  • Eravacycline
  • Ertapenem
  • Erythromycin
  • Famciclovir
  • Fidaxomicin
  • Fluconazole
  • Flucytosine
  • Foscarnet
  • Fosfomycin
  • Ganciclovir
  • Gentamicin
  • Glecaprevir/ Pibrentasvir
  • Ibrexafungerp
  • Imipenem-cilastatin
  • Imipenem-cilastatin-relebactam
  • Isavuconazole
  • Itraconazole
  • Ivermectin
  • Ledipasvir/sofosbuvir
  • Lefamulin
  • Letermovir
  • Levofloxacin
  • Linezolid
  • Maribavir (Livtencity)
  • Meropenem
  • Meropenem-vaborbactam
  • Metronidazole
  • Methenamine
  • Micafungin
  • Minocycline
  • Molnupiravir (Lagevrio)
  • Moxifloxacin
  • Nafcillin
  • Nitrofurantoin
  • Omadacycline
  • Oritavancin
  • Oseltamivir
  • Oteseconazole (Vivjoa)
  • Oxacillin
  • Paxlovid (nirmatrelvir/ ritonavir)
  • Penicillin
  • Penicillin Skin Test
  • Phenazopyridine
  • Piperacillin-tazobactam
  • Plazomicin
  • Polymyxin B
  • Posaconazole
  • Quinupristin-dalfopristin
  • Remdesivir (Veklury)
  • Ribavirin
  • Rifabutin
  • Rifampin
  • Secnidazole
  • Sofosbuvir/ velpatasvir/ voxilaprevir
  • Sotrovimab (Xevudy)
  • Sulfadiazine
  • Sulfamethoxazole-Trimethoprim (Bactrim)
  • Tedizolid
  • Telavancin
  • Tigecycline
  • Tobramycin
  • Tocilizumab
  • Valacyclovir
  • Valganciclovir
  • Vancomycin
  • Voriconazole
  • Zidovudine
  • Zoster vaccine recombinant, adjuvanted (Shingrix)

Recent

  • Five Common Financial Mistakes To Avoid As A Pharmacist
  • Five Things I Learned From #ASMicrobe 2022 – Through Twitter
  • Going From A To Z With Antibiotic Toxicities
  • IV Push Antibiotics: Practical Insights & Tips From The Front Lines
  • Reality Versus Expectation: Being a Specialty Pharmacist

Search

Copyright 2016-2020 By Charlie Rose, LLC © · IDStewardship.com · Copyright · Privacy Policy · Terms · Contact